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Bob #9 I appreciate all of your contributions to my better understanding

In this literature review, tobacco use refers to any use of any nicotine-containing tobacco product, i.e., cigarettes, cigars, smokeless tobacco, and electronic cigarettes

LPO is a key component of the innate immune system in the airways, and its inhibition leads to elevated H2O2 levels, which disrupts mitochondrial homeostasis, promotes epithelial cell senescence, and enhances the production of pro-inflammatory cytokines (Santiago et al., 2024)

However, campaigners and analysts questioned whether e-cigarettes or other products such as the iQos would ever replace cigarettes