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216 In dextran sulfate sodium (DSS)-induced colitis mice, a lack of phenazine biosynthesis-like domain-containing protein (PBLD) in the colon epithelium led to excessive activation of NF-B

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This is accompanied by a shift in macrophage populations, with a higher number of pro-inflammatory M1 macrophages and reduced anti-inflammatory M2 macrophages in Hunner lesions

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