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The GP reaction is: 2GSH + H 2 O 2 GS-SG + 2H 2 O where GSH represents reduced monomeric glutathione, and GS-SG represents glutathione disulfide

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In addition, further exploration is necessary to identify the molecular switches of tumor cells that activate alternative metabolic pathways (e.g., Glycolysis or Fatty acid oxidation) in response to glutamine deprivation