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These claims are used to describe 1) that the product is made with nicotine created in a lab (i.e., tobacco-free nicotine, also known as synthetic nicotine or non-tobacco nicotine), or 2) that the product contains no tobacco leaf (i.e., tobacco-free or tobacco leaf-free)

The key phenolic acids identified were chlorogenic acid, neochlorogenic acid, cryptochlorogenic acid, and 3-feruloylquinic acid

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Researchers surveyed a representative sample of 1,280 18- to 24-year-olds through an online questionnaire between Aug