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31 In a trial evaluating semaglutide for weight loss, the incidence of acute pancreatitis was still low (3 of 1,306 participants) despite a higher dose and more significant weight loss, but none of the 655 individuals in the placebo group developed pancreatitis

Currently there is no preventive therapy for noninfectious uveitis

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"However, more data from large-scale randomised trials and longer treatment and follow-up periods are needed to establish the long-term efficacy of GLP-1 RAs, as well as future studies exploring whether these medications might be useful for the direct treatment of mental health disorders." In the UK, the injections are licensed for those with a body mass index of 27 or more but they are tightly rationed by the NHS