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Unexpectedly, a recent study reported that lung DCs induced intestinal immunity responses against a highly pathogenic strain of Salmonella via upregulating the gut-homing integrin 47 and inducing T-cell migration to the intestinal tract ( Interleukin-6 (IL-6) exerts a pivotal role in regulating many cellular process and has been implicated in the pathogenesis of various inflammatory disorders such as COPD and IBD (Tulic et al., 2016)

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