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A 2016 study conducted by the University of Southern California and published in the journal Pediatrics came to a sobering conclusion: Older teens who try electronic cigarettes (e-cigarettes) are six times more likely to try combustible cigarettes within two years, compared to those who have never used the devices

Sensitivity analyses using propensity score matching were conducted for selected pairwise contrasts to assess the robustness of the regression findings to imbalance in measured covariates between exposure groups

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The director Rupert Wyatt felt the role was underwritten and cast Larson to lend heft to it