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Conflict of interest The authors have no conflicts of interests related to this publication

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demonstrated the ability of efflux transporters to hinder drug delivery to the CNS even in the presence of MRgFUS 210

Tips for reducing injection site reactions: Rotate injection sites with every dose abdomen, thigh, or upper arm Allow the pen to reach room temperature before injecting Do not inject into areas of redness, bruising, or hardened skin Use a slow, steady injection technique From Our Medical Team Janna Goldfeld, PA-C Rotating injection sites is one of the simplest ways to reduce discomfort