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yet are typically less successful than other populations in their quit attempts
However, damage such as gum recession and bone loss may be permanent
Treatment with nicotine also activates NF-B signaling and increases proliferation of endothelial and smooth muscle cells [284]
The high incidence of oral cancer could be attributed to a combined effect of specific risk factors such as tobacco consumption, exposure to carcinogenic agents, and insufficient access to newly developed diagnostic aids that delays the diagnosis of oral cancer (Sharma et al., 2018)
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