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10.1002/(SICI)1096-9861(19990111)403:2 3.0.CO;2-5 70 MirasA

Individual project commitments within that total include a $4.1 billion fill-finish facility at its Clayton, North Carolina campus, representing one of the largest single manufacturing investments in Novo Nordisk's history, and adding 1.4 million square feet of aseptic manufacturing and finished production space

PMID 24573738

Various other research studies, like one done by the American Journal of Professional Nourishment in 2000, indicate that this number might be even greater, with up to 39 percent of the populace possibly enduring from a vitamin B12 deficiency