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(2023d, May 24)

960 Preclinical studies have shown that metformin enhances chemotherapy sensitivity by disrupting the HIF-1/PKM2 pathway, inducing apoptosis, and preventing epithelialmesenchymal transition

As regulatory requirements become more stringent and consumer expectations for product quality and transparency continue to rise, the competitive advantage favoring larger, better-capitalized manufacturers is expected to intensify, potentially resulting in further consolidation within the industry

However, excessive intake of unsaturated FAs may increase the production of pro-inflammatory lipid mediators and potentially worsen renal injury (Zhang et al., 2025