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This article is part of the Topical Collection on Asthma Rights and permissions About this article Cite this article Dai, X., Bui, D.S

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This chronic inflammation degrades the tight junctionsthe protein structures that glue intestinal cells togetherleading to a condition known as intestinal permeability, or "leaky gut." When the gut barrier is compromised, it loses its ability to selectively filter what enters the bloodstream