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For example, the NHS says: Smoking doesn't directly cause high blood pressure but it puts you at much higher risk of a heart attack and stroke

Only one cross-sectional study reported that non-smoker current vapers had faster lung aging than never smokers, and the effect was similar to that seen among non-vaper current smokers, suggesting that non-smoker current vapers had an increased risk of age-related lung disease, including cancer 32

There is no known link that nicotine replacement therapy causes cancer