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Combinative treatment of -elemene and cetuximab could induce ferroptosis of KRAS-mutant colorectal cancer cells (CRC) by iron-dependent ROS accumulation, GSH depletion, lipid peroxidation, upregulation of HO-1 and transferrin, and downregulation of negative regulatory proteins for ferroptosis (GPX4, SLC7A11, FTH1, glutaminase, and SLC40A1), thus inhibiting tumor growth and lymph node metastases in vivo ( Curcuma zedoaria [Zingiberaceae
However: Caloric Impact : Alcohol contains 7 calories per gram (empty calories) that can interfere with weight loss Tolerance Changes : GLP-1 medications may affect alcohol tolerance
(PubMed) Ma F, Li Q, Zhou X, et al