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Epithelial restitution and barrier integrity changes would be expected to manifest as improvements in intestinal permeability assays and endoscopic healing scores, such as Simple Endoscopic Score for Crohns Disease [SES-CD] or Mayo Endoscopic Score (82)

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Synthetic peptides are designed to target the biological process through which the body produces melanin, producing more significant reported results

Most patients begin on a low starter dose (typically 0.25 mg weekly) and increase by 0.25 mg increments every 4 weeks until reaching a therapeutic dose of 1 to 2.4 mg weekly