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[DOI] [PMC free article] [PubMed] [Google Scholar] 453.Widmann C., Dolci W., Thorens B

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The body has a really complex mechanism of trying to defend its weight from times when food was not as plentiful as it is now losing weight was really quite a major survival issue for humans, so the body naturally has some very strong physiological mechanisms to ensure your body weight stays pretty constant. Ozempic hijacks those mechanisms, or receptors which tell you when youre hungry, Holt explains, allowing you to eat less to lose weight