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They were originally developed as a treatment for type 2 diabetes

Thigh : Choose an area on the front or outer thigh, avoiding bony areas

In its National Poison Data System alert, Americas Poison Centers noted that some people reported accidentally taking 10-times the recommended dose due to confusing measurement units while using a syringe. And people who are eager to lose extra weightbefore a wedding or a vacation, for examplemay choose to self-administer a higher-than-recommended dose, said Arthur Caplan, a bioethics professor at New York Universitys Grossman School of Medicine

The typical use case is with: knee, hip, shoulder, rotator cuff, and low back issues (source)