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Phase III Phase III does not offer funding from the SBIR program directly, but instead provides the contractual justification for the government to buy the capability developed in phase I and II directly without further competition because it was developed, at least in part, with government funding under the SBIR program

The new model a simple nasal spray, with no bruising, no pain and no clinic visit required removes that barrier entirely

Explored as a possible aid for recovery and lean-mass preservation in frail or catabolic populations, though a Merck-sponsored Phase 2b trial in elderly hip-fracture patients (Adunsky et al., 2011, Archives of Gerontology and Geriatrics, PMID 21067829) was halted early over a cardiac safety signal rather than demonstrating a clear functional benefit

Semaglutide remained chemically stable in all of the co-formulations (comprising 11.25-15% w/v HP-B-CD)