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Adult users often compare flavor strength, smoothness, tobacco blend, and overall smoking feel between the two brands

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It is known to increase the risk of inflammatory bowel disease like IBD." Dr Rohan Badave, Consultant - Medical Gastroenterology, Manipal Hospital, Goa, echoes the concern, "Tobacco use (smoking or chewing) can alter the balance of gut bacteria, potentially contributing to bloating, flatulence, abdominal discomfort, and altered bowel habits." Experts say this microbial imbalance may explain why many tobacco users frequently complain of gas, abdominal discomfort, unpredictable bowel movements, and persistent digestive uneasiness

The results of this systematic review and meta-analysis are consistent with a substitution effect between cigarettes and ENDS, such that price increases in cigarettes were associated with higher demand for ENDS