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Hand Exp Pharmacol

While contradictory results have been published for acetaminophen glucuronidation, a subgroup of subjects with Gilberts syndrome shows a reduction in excretion of APAP glucuronide and a concomitant increase in the elimination of the CYP450 APAP metabolites [22,25,96,98,99]

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Interestingly, a study comparing the migration of TH1 cell line across a monolayer of mouse cell line bEnd5 or primary brain mouse endothelial cells revealed a longer crawling of T cells in bEnd5 and a decrease of diapedesis in primary cells (Steiner et al., 2011)