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-Amyloid protein induces mitophagy-dependent ferroptosis through the CD36/PINK1/Parkin pathway leading to bloodbrain barrier destruction in Alzheimers disease

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Furthermore, animal research has found that extremely high doses of alpha-lipoic acid may promote oxidation, alter liver enzymes, and place strain on liver and breast tissue (38, To date, very few studies have looked at the safety of alpha-lipoic acid in children and pregnant women

Nat Commun 8:1177 Arbour KC, Jordan E, Kim HR, Dienstag J, Yu HA, Sanchez-Vega F, Lito P, Berger M, Solit DB, Hellmann M, Kris MG, Rudin CM, Ni A, Arcila M, Ladanyi M, Riely GJ (2018) Effects of co-occurring genomic alterations on outcomes in patients with KRAS-mutant non-small cell lung cancer