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That harsh hit can trigger headaches

Regul Toxicol Pharmacol 93:1433 Farsalinos KE, Yannovits N, Sarri T, Voudris V, Poulas K, Leischow SJ (2018) Carbonyl emissions from a novel heated tobacco product (IQOS): comparison with an e-cigarette and a tobacco cigarette

Heat-not-burn products are different from e-cigarettes because they use real tobacco, not the flavored liquid nicotine typically found in e-cigarettes