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"I work with many patients who are addicted to nicotine, and the vast majority have never smoked a cigarette." Puls said this pattern is especially common among adolescents and young adults and is concerning because cigarettes typically deliver about 1 to 2 milligrams of nicotine, while some vape products can contain 20 to 60 milligrams

Examinations of this brain activity also could lead to improved personalized intervention strategies for smokers

Second, an increasingly larger share of combustible and electronic use was brand placement

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