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Common nutrients to monitor include: Vitamin D (deficient in over 50 percent of patients with obesity at baseline) Vitamin B12 (2 to 18 percent deficiency rate) Iron (up to 45 percent inadequacy) Calcium and magnesium (over 50 percent inadequate intake) Zinc (24 to 28 percent inadequacy) Thiamine and other B vitamins A daily multivitamin may be reasonable for individuals with substantial appetite reduction

2012;302:H24282438

Adjusted regression analysis indicated an approximately 1% additional monthly BMI reduction with GLP-1 therapy ( = 1.08%, p = 0.001)

The 2023 American Diabetes Association guidelines recommend GLP-1RAs or sodium-glucose cotransporter-2 inhibitors (SGLT-2i) with cardiovascular benefits as one of the indispensable medications for the treatment of T2DM, along with significant weight loss, in addition to metformin therapy