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Graves Disease In Graves disease, the immune system also creates thyroid antibodies, but these antibodies activate thyroid-stimulating hormone receptor (TSHR), producing hyperthyroidism

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The symptoms of a more severe deficiency include anemia, which presents as fatigue, pale skin color, shortness of breath, and lightheadedness

Physical Function Results WOMAC physical function subscale (baseline 5.8 points, scale 010): Both retatrutide doses produced reductions in the physical function subscale exceeding 70% meaning patients could perform daily activities with substantially less difficulty than at baseline