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however this threshold varies in the literature Imaging Radiographs look for joint dislocations/subluxations kyphoscoliosis Echocardiogram cardiac evaluation with echo is mandatory in the workup up to 1/3 of patients have aortic root dilatation Labs Diagnosed by collagen typing of skin biopsy Treatment Nonoperative physical therapy, orthotics, supportive measures for pain Operative arthrodesis posterior spinal fusion Create a free account or log in to see the cards.

Serious concerns with unregulated/high-dose use: infections from non-sterile settings, kidney or liver stress at very high doses over time, and (rarely) thyroid disruption

When taken early in treatment, evidence shows that supplemental vitamin B12 may enhance the impact of antidepressants and delay depression onset