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The study reveals that the SLC25A39 transporter, which imports glutathione into mitochondria, is essential for cancer spread, and elevated SLC25A39 expression correlates with poorer survival outcomes in breast cancer patients, suggesting potential therapeutic targeting opportunities

Tretinoin (0.1%) represents the most potent topical option available

doi: 10.1038/s41598-018-29313-w [DOI] [PMC free article] [PubMed] [Google Scholar] 96.Millman AC, Salman M, Dayaram YK, Connell ND, Venketaraman V

APAP toxicity, whether resulting from a single overdose or repeated supratherapeutic ingestion, progresses through four phases: preclinical toxic effects (phase one), hepatic injury (phase two), hepatic failure (phase three), and recovery (phase four)