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doi: 10.3389/fped.2020.591132 121 WangMYZhaoRGaoLJGaoXFWangDPCaoJM

Adverse Reactions The most commonly reported adverse reactions include injection site reactions, arthralgia, pain in extremity, myalgia, and peripheral edema

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Liraglutide also decreased angiotensin II-induced oxidative stress by increasing the levels of NADPH oxidase activity, increasing endothelial NO availability, and reducing immune cell infiltration by reducing the levels of F4/80 (a macrophage marker F4/80 with proinflammatory properties) expression in cardiac tissue thus reducing the overall level of oxidative stress in hypertensive heart disease