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17 Consequently, the elevated histone Kla upregulates pluripotent genes such as Oct4, Sall4, and Mycn and promotes somatic cell reprogramming and pluripotency, revealing a glycolysis-driven signaling cascade linking the epigenome and metabolome in cell-fate determination

That also means the calorie deficit tends to be more aggressive, which makes the muscle preservation conversation even more important on this drug

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