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Interestingly, previous studies have shown that pancreatic islets from diet-induced obese adult mice display decreased glucose-stimulated insulin secretion when treated with semaglutide, while no effect of semaglutide was detected on the islets of AIN93-fed mice [44]

Author contributions Luis Antonio Diaz: Conceptualization, Writing - Original Draft, Writing - Review and Editing, Juan Pablo Arab: Writing - Original Draft, Writing - Review and Editing

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Research suggests KPV may influence inflammatory pathways such as NF-kB and MAPK signaling and may reduce production of certain pro-inflammatory cytokines in experimental models