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Mol Pharmacol 46:909914 Kim SK, Woodcroft KJ, Khodadadeh SS, Novak RF (2004) Insulin signaling regulates gamma-glutamylcysteine ligase catalytic subunit expression in primary cultured rat hepatocytes

Diagnostic features: The endothelial lining cells have a moderate pleomorphism

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It selectively enhances early insulin release providing excellent meal time glucose control while reducing total insulin exposure [122] Biguanides: These agents dont cause hypoglycemia and are thus called euglycemic agents