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Further studies are needed to elucidate the precise mechanisms and potential therapeutic implications of targeting UA in the context of misfolded protein-related neurodegenerative diseases

Conversely, NPs of silver, TiO 2 , zinc oxide (ZnO), copper, and nickel induced oxidative stress in male reproductive organs (144147)

Its primary symptoms include pelvic pain, which may manifest as dysmenorrhea, dyspareunia, or chronic pelvic pain, often accompanied by overlapping symptoms (e.g., urinary or gastrointestinal manifestations), complicating clinical diagnosis (Parasar et al., 2017)

This enzymatic barrier explains why many patients report minimal clinical benefit from standard oral supplements