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Hamadi SA, Mohammed MM, Aljaf AN, Abdulrazak A

The design bet behind a GLP-1/glucagon dual agonist is that GLP-1s insulinotropic, appetite-suppressing, glucose-lowering effects can be used to offset the hyperglycemic tendency of glucagon, while glucagons thermogenic and hepatic-lipid effects add weight-loss and liver-directed benefits that GLP-1 alone does not deliver

It is also being investigated in combination with other investigational or approved compounds , such as semaglutide (a GLP-1 receptor agonist), under the name CagriSema

La respuesta se evala a los 3-6 meses, con reevaluaciones peridicas cada 3-6 meses para monitorizar eficacia, control glucmico y efectos adversos