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S13C and D), further validating OPA1 as a potential pharmacological target

Zonulin, a key regulator of tight junction integrity in intestinal epithelial cells, has been implicated in these processes [70]

The inclusion criteria consisted of original research articles, clinical trials, and systematic reviews published in peer-reviewed journals during the designated period

Detailed kinetic information is available on amino acid transporters [44, 45] and on the high and low affinity transporters of GSH and GSSG [32, 39, 46] and we chose our kinetics parameters from this literature