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NAC may be useful when: Cysteine availability may be limiting The goal is to support internal glutathione synthesis Direct glutathione is poorly tolerated A clinician has identified a relevant medical or nutritional reason NAC does not guarantee that glutathione production will increase adequately

Lack of effect of oral sulforaphane administration on nrf2 expression in COPD: a randomized, double-blind, placebo-controlled trial

Ans) Nausea is a common side effect of the medicine but not at severity