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R., Loni A., Canham L
For example, a kainite-model of TLE showed that seizures increased the steady-state mitochondrial ROS levels in the forebrain, which caused deficits in mitochondrial respiration, exemplified by the significant reduction of oxygen consumption by hippocampal neurons ( Discussion The complex and elaborate nature of cortical development, during which a large amount of ATP is produced and utilized, necessitates a deeper understanding of metabolized macromolecules and the mitochondria
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