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29,30 Genetic testing for mutations in SCN9A and SCN10 (which code for the Nav1.7 and Nav1.8 sodium channels, respectively) is commercially available and may be considered for those with a family history of neuropathic pain in the feet or for young, otherwise healthy patients

Statistical significance for comparisons between treated and control cell samples was determined by the unpaired t -test using Statistica 10.0 PL software

Patients typically experience: Appetite reduction within 12 weeks Steady weight loss within the first month Visible body changes within 812 weeks Typical outcomes include 10-25+ pounds in the first few months

References Morgan E, Arnold M, Gini A, Lorenzoni V, Cabasag CJ, Laversanne M, et al