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In Diverse Therapeutic Strategies Targeting TMAO, we curated the most pertinent preclinical and in vitro studies on TMAO, emphasizing findings associated with TMAO-induced cell death to deliver a thorough summary of its role in the development and progression of diseases along the gut-organ (lung, pancreas, heart, kidney, and brain) axis

Thus, it would also be of interest to develop future experiments to determine whether heat stress significantly impacts the expression levels of specific genes in both in vitro and in vivo models