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Abdominal Cramping or Pain Semaglutide use has been associated with abdominal pain and dyspepsia in research, with a report of a 61-year-old male being diagnosed with gastric pneumatosis following a dosage of 4 mg/week (17)

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Patients may notice blood in their stool as bright red streaks, dark tarry stools (melena), or blood mixed with diarrhea

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