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POMC-derived peptides including adrenocorticotropin (ACTH), alpha melanocyte stimulating hormone (-MSH), -MSH and -endorphins, MC1R, adrenergic and cholinergic agents, and growth factors, cytokines, or nitric oxide (NO) secreted in the local microenvironment are all involved in the regulation of melanogenesis [6]

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Combination of curcumin with Nn-butyl haloperidol iodide inhibits hepatocellular carcinoma malignant proliferation by downregulating enhancer of zeste homolog 2 (EZH2)-lncRNA H19 to silence Wnt/-catenin signaling

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