andrew huberman semaglutide What is GLP-1 & How Does It Reduce Appetite & Promote Weight Loss? Neuroscientist Andrew Huberman believes GLP-1s

Contact your healthcare provider promptly if you experience: Severe or persistent heartburn unresponsive to over-the-counter antacids or lifestyle modifications Difficulty swallowing (dysphagia) or painful swallowing (odynophagia), which may indicate esophageal inflammation or stricture Persistent nausea and vomiting that prevents adequate oral intake or leads to dehydration Vomiting blood (hematemesis) or material resembling coffee grounds Black, tarry stools (melena) or visible blood in stool Severe abdominal pain, particularly if localized to the upper abdomen or radiating to the back (stop medication immediately if pancreatitis is suspected) Right upper quadrant pain, fever, or yellowing of skin/eyes, which may indicate gallbladder disease Unintentional weight loss beyond expected therapeutic effects New or worsening chest pain (call 911 if concerning for heart attack), especially if accompanied by shortness of breath These symptoms may indicate complications such as erosive esophagitis, gastrointestinal bleeding, pancreatitis, or gastroparesis

Other side effects can include fatigue, headache, hair loss, vomiting and burping

Oral semaglutide mimics this hormone, enhancing its effects

According to the FDA prescribing information for tirzepatide, constipation is reported as a common gastrointestinal adverse effect, though it occurs less frequently than nausea, diarrhea, and vomiting