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These include: Lifestyle interventions (dietary advice, physical activity programmes) Licensed pharmacotherapy such as orlistat, or GLP-1 receptor agonists including semaglutide 2.4 mg (Wegovy, NICE TA875) or tirzepatide (Zepbound) where clinically indicated and available Referral to tier 3 or tier 4 weight management services , including bariatric surgery assessment where appropriate Information on NHS weight management services and eligibility for licensed treatments is available via the NHS website and NICE guidance

Find out which supplements help for varicose veins and chronic venous insufficiency, including citrus bioflavonoids and grape seed extract

Gastrointestinal conditions Patients with pre-existing gastrointestinal conditions need particular caution with tirzepatide

Estimates for observed Prescriptions for parenteral B12 It is clear that there is a considerable excess of observed over expected